{"id":106,"date":"2023-01-11T12:11:28","date_gmt":"2023-01-11T12:11:28","guid":{"rendered":"https:\/\/neuroblastoma.org\/eng\/?page_id=106"},"modified":"2023-05-05T10:32:55","modified_gmt":"2023-05-05T10:32:55","slug":"about-neuroblastoma","status":"publish","type":"page","link":"https:\/\/neuroblastoma.org\/eng\/about-neuroblastoma\/","title":{"rendered":"About Neuroblastoma"},"content":{"rendered":"\t\t
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About Neuroblastoma<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Disease Information<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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This area is dedicated in particular to patients and family members as aims to provide main indications and informations on the diseases that are at the heart of our focus, on the disgnosis and therapies used.
We firmly believe that information promotes a peaceful relationship between families, patients and our doctors, creating a fundamental therapeutic alliance in order to deal with the disease in a resolute and calm way.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Help us fund cutting-edge research projects to save children with Neuroblastoma<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tDonate now<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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What is Neuroblastoma?<\/h2>

Neuroblastoma is a very aggressive childhood cancer: in Italy affects about 130 children every year. It is a rare tumor and represents the primary cause of death by illness for the pre-school age group.
Neuroblastoma is a subtle tumour with similar symptoms to influence ones: for this reason is often diagnosed late, when already presents itself with metastasis and healing it becomes really difficult.
Neuroblastoma is an excellent study model: it is in fact considered \u201ca group of tumours\u201d since holds all the genetic characteristics of nearly all paediatric solid tumours. Finding a permanent cure for Neuroblastoma means find a cure for all paediatric tumours.
During these years important progress has been made thanks to the research supported by the Association: we went from 25% in 90\u2019s to 65% of today chance of survival at 5 years after the diagnosis for favorable prognosis cases and from 8 to 35-40% for children with aggressive cancer and poor prognosis. Every year in Italy it affects about 130 children and teenagers.<\/p>

Neuroblastoma is a childhood tumor that affects children from 0 to 10 years of age. Along with brain tumors Neuroblastoma is considered the first cause of death and the third neoplasm by frequency after leukemias and Pediatric Brain Tumors.
The term Neuroblastoma refers to a group of malignant tumors more frequent in the first years of life, originating from the remnants of autonomic nervous system that develops during embryonic life.
This tumor originates from neuroblasts, cells located in sympathetic nervous system, a series of neuronal bundles spread throughout the body that control some involuntary functions such as breathing, digestion and heartbeat. Neuroblasts are immature or developing cells that are located in nerves and are widespread throughout the body: neck, adrenal glands, chest, spine.
For this reason Neuroblastoma can arise in different parts. Most cases of Neuroblastoma occur at adrenal glands level, which are located above kidneys, or in the nerve ganglia present in abdomen.
From the clinical point of view Neuroblastoma has some peculiarities:
Prognosis is very good in children under the year of life, regardless of metastic disease extent.
In the first year of life the disease can regress on it\u2019s own even if disseminated.
In older children prognosis is decidedly unfavorable.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Diagnosis<\/div>\n\t\t\t\t\t\t\t\t\t
How to cure it<\/div>\n\t\t\t\t\t\t\t\t\t
Research<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t
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Diagnosis<\/div>\n\t\t\t\t\t